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Finally, migraine support you deserve.

MigreLief provides nutritional support for migraine sufferers.

To Begin

Take one caplet every morning and evening for best results.

Days 1-90

Give your body time to absorb the essential nutrients to feel the benefits.

90 Days Later

Feel real results in 90 days or get your money back.

Clinically studied ingredients. Doctor recommended.

  • Original patented triple-therapy formula is widely recommended by neurologists.
  • Effective ingredients: Magnesium, Riboflavin (Vitamin B-2), and Puracol® Feverfew.*
  • Safe and effective for teen & adult migraine sufferers*

Clinical studies show the three key ingredients of MigreLief support nutritional imbalances within our bodies to help take control of headaches and migraines.

Trusted by thousands

4.9 out of 5.0 stars | Based on 4,150 Reviews

I should have purchased this sooner

This has been a true lifesaver, and I was a sceptic at first. Like many others, I’ve tried everything and MigreLief has been the ONLY thing that has helped.

| Christine A.
Migrelief WORKS and is an answer to prayer

This stuff is the only thing that helps. I couldn't function without MigreLief. They're an answer to prayer.

| Emily P.
A major difference

I'm 23, and I've had migraines since I was a kid. It runs in the family. I started taking these a few months ago, and they've made a huge difference!

| Hayley L.
Puracol® Feverfew

Found only in MigreLief, is a proprietary blend of feverfew, a plant known for its health benefits.


Two forms of magnesium that are proven to be helpful in daily amounts to control blood vessel spasms.

Riboflavin (Vitamin B-2)

Though we need riboflavin for health, our bodies can't produce it; so we obtain it through food or supplements.

Safe and effective nutritional support for migraine sufferers.

Doctor Recommended
Backed by Science


Backed by science

MigreLief® was researched and developed by Akeso Health Sciences' Chief Scientific Officer, Curt Hendrix, MS, CCN, CNS, a research scientist who holds degrees in chemistry and clinical nutrition and is a Clinical Nutrition Specialist.

  1. Brown D, Gaby A, Reichert R. Clinical Applications of Natural Medicine–Migraine. NPRC Condition-Specific Monograph Series, 1997.
  2. Lawrence Review of Natural Products, September 1994.
  3. Awang DVC. Herbal Medicine, Feverfew. Canadian Pharm J 1989; 122:266-70.
  4. Heptinstall S, Awang DVC, Dawson BA, et al. Parthenolide Content and Bioactivity of Feverfew (Tanacetum parthenium). Estimation of Commercial and Authenticated Feverfew Products. J Pharm Pharmacol 1992; 44:391-5.
  5. Pugh WJ, Sambo K. Prostaglandin Synthetase Inhibitors in Feverfew. J Phrm Pharmacol 1988; 40-743-5
  6. Heptinstall S, White A, Williamson L, Mitchell JRA. Extracts of Feverfew Inhibit Granule Secretion in Blood Platelets and Polymophonuclear Leukocytes. Lancet 1985; i:1071-4.
  7. Makheja AN, Bailey JM. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostagland Leukotrienes Med 1982;8:653-60.
  8. Sumner H, Salan U, Knight DW, Hoult JRS. Inhibition of 5-Lipoxygenase and Cyclo-oxygenase in Leukocytes by Feverfew. Biochem Pharmacol 1992;43:2313-20.
  9. Johnson ES, Kadam NP, Hylands DM, Hylands PF. Efficacy of Feverfew As prophylactic Treatment of Migraine. British Med J 1985; 291:569-73.
  10. Murphy JJ. Heptinstall S, Mitchell JRA. Randomized Double-Blind Placebo-Controlled Trial of Feverfew in Migraine Prevention. Lancet 1988; ii:189-92.
  11. Altura BM. Calcium Antagonist Properties of Magnesium: Implications for Anti-migraine Actions. Magnesium 1985; 4:169-75.
  12. Ramadan NM, Halvorson H, Vande-Linde A, et al. Low Brain Magnesium in Migraine. Headache 1989; 29:590-93.
  13. Weaver K. Magnesium and Migraine. Headache 1990; 30:168.
  14. Faccinetti F, Sances G, Borella P, et al. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intra-cellular Magnesium. Headache 1991; 31:298-304.
  15. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of Migraine with Oral Magnesium: Results from a Prospective, Multi-Center, Placebo-Controlled and Double-Blind Randomized Study. Cephalalgia 1996; 16:257-63.
  16. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the Prophylaxis of Migraine Cephalalgia 1996;16;436-40
  17. Schoenen J, Lenaerts M, Bastings E. High-dose Riboflavin as a Prophylactic Treatment of Migraine: Results of an Open Pilot Study. Cephalalgia 1994l14:328-9
  18. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomised controlled trial. Neurology 1998; 50: 46670.
  19. Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G. High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 2004 Jul;11(7):475-7.
  20. Maria Condò, Annio Posar, Annalisa Arbizzani and Antonia Parmeggiani Riboflavin prophylaxis in pediatric and adolescent migraine. The Journal of Headache and Pain: Volume 10, Number 5 / October, 2009.

MigreLief “Original” – Effective for adults and teens ages 13 and older

Take 1 caplet in the morning and 1 caplet in the afternoon or evening with food. Allow six to seven hours between servings.

Continue daily use after 90 day build-up period to maintain benefits. Many see benefits starting within a few days.

  • Riboflavin (Vitamin B-2) can cause urine to become bright yellow. This is normal and harmless.
  • Although rare, some individuals experience transient (short term) diarrhea when taking magnesium.
  • Like most dietary supplements, use of MigreLief should be discontinued one week before any surgery.

CAUTION: Not for use during pregnancy, during lactation or by children under 13 years of age. (For children age 2-12 consider Children's MigreLief)