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Reclaim your life with MigreLief

For over 25 years MigreLief has been providing migraine sufferers with foundational and targeted nutritional support that truly makes a difference. 

To Begin

Take one caplet every morning and evening for best results.

Days 1-90

Give your body time to absorb the essential nutrients to feel the benefits.

90 Days Later

Feel real results in 90 days or get your money back.

Tried, true, and trusted drug‑free option.

Recommended by neurologists and top headache clinics since 1997, MigreLief’s original patented triple-therapy formula is designed to meet the unique nutritional needs and imbalances that many migraine sufferers have in common

  • Magnesium (combination of two sources)
  • Riboflavin (vitamin B-2)
  • Puracol feverfew (whole leaf and a special extract)

What our customers are saying

4.9 out of 5.0 stars | Based on 4,150 Reviews

I have been using MigreLief for several years and it has helped maintain worry free days!!

| Renee C.

MigreLief is a crucial part of my life. I wouldn't go a day without it.

| Margaret P.

MigreLief is a blessing. Recommend by my neurologist. It's been a huge help.

| Stella S.
Rated 4.8 out of 5 stars
Based on 1,342 reviews
96%would recommend these products
Total 5 star reviews: 1.1k Total 4 star reviews: 155 Total 3 star reviews: 42 Total 2 star reviews: 5 Total 1 star reviews: 2
1,342 reviews
  • Lisa B.
    Verified Buyer
    MigreLief Original Formula
    MigreLief Original Formula
    I recommend this product
    Rated 5 out of 5 stars
    My migraine experience

    It worked wonderful

  • eller k.
    Verified Buyer
    MigreLief Original Formula
    MigreLief Original Formula
    I recommend this product
    Rated 5 out of 5 stars

    Love it

  • Brenda S.
    Verified Buyer
    MigreLief Starter Pack
    MigreLief Starter Pack
    I recommend this product
    Rated 5 out of 5 stars
    Migraña cronica

    Ya e comprado casi 6 meses y son las mejores.

  • Tetiana M.
    Verified Buyer
    MigreLief Original Formula
    MigreLief Original Formula
    I recommend this product
    Rated 5 out of 5 stars
    surprisingly good result within a short time

    I found it surprisingly good. I didn't expect much from the supplements, but it really works!

  • Sandra G.
    Verified Buyer
    MigreLief Original Formula
    MigreLief Original Formula
    I recommend this product
    Rated 5 out of 5 stars
    MigreLief Original Formula

    So far so good. 😊

Reviews LoadedReviews Added
Puracol® Feverfew

Unique to MigreLief, a powerful blend of a special extract + whole leaf feverfew, a plant known for its health benefits for centuries.


Two forms of magnesium that inhibit platelet aggregation and blood vessel spasms for neurological comfort.

Riboflavin (Vitamin B-2)

Riboflavin supports healthy brain function by promoting energy metabolism and blood flow, while also regulating neurotransmitters

MigreLief works for you or your money back!

Try MigreLief risk-free today with our 90-day money-back satisfaction guarantee and find out why it’s the only migraine supplement you’ll ever need!

Nothing works like MigreLief

Doctor Recommended
Backed by Science


Backed by science

MigreLief® was researched and developed by Akeso Health Sciences' Chief Scientific Officer, Curt Hendrix, MS, CCN, CNS, a research scientist who holds degrees in chemistry and clinical nutrition and is a Clinical Nutrition Specialist.

  1. Brown D, Gaby A, Reichert R. Clinical Applications of Natural Medicine–Migraine. NPRC Condition-Specific Monograph Series, 1997.
  2. Lawrence Review of Natural Products, September 1994.
  3. Awang DVC. Herbal Medicine, Feverfew. Canadian Pharm J 1989; 122:266-70.
  4. Heptinstall S, Awang DVC, Dawson BA, et al. Parthenolide Content and Bioactivity of Feverfew (Tanacetum parthenium). Estimation of Commercial and Authenticated Feverfew Products. J Pharm Pharmacol 1992; 44:391-5.
  5. Pugh WJ, Sambo K. Prostaglandin Synthetase Inhibitors in Feverfew. J Phrm Pharmacol 1988; 40-743-5
  6. Heptinstall S, White A, Williamson L, Mitchell JRA. Extracts of Feverfew Inhibit Granule Secretion in Blood Platelets and Polymophonuclear Leukocytes. Lancet 1985; i:1071-4.
  7. Makheja AN, Bailey JM. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostagland Leukotrienes Med 1982;8:653-60.
  8. Sumner H, Salan U, Knight DW, Hoult JRS. Inhibition of 5-Lipoxygenase and Cyclo-oxygenase in Leukocytes by Feverfew. Biochem Pharmacol 1992;43:2313-20.
  9. Johnson ES, Kadam NP, Hylands DM, Hylands PF. Efficacy of Feverfew As prophylactic Treatment of Migraine. British Med J 1985; 291:569-73.
  10. Murphy JJ. Heptinstall S, Mitchell JRA. Randomized Double-Blind Placebo-Controlled Trial of Feverfew in Migraine Prevention. Lancet 1988; ii:189-92.
  11. Altura BM. Calcium Antagonist Properties of Magnesium: Implications for Anti-migraine Actions. Magnesium 1985; 4:169-75.
  12. Ramadan NM, Halvorson H, Vande-Linde A, et al. Low Brain Magnesium in Migraine. Headache 1989; 29:590-93.
  13. Weaver K. Magnesium and Migraine. Headache 1990; 30:168.
  14. Faccinetti F, Sances G, Borella P, et al. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intra-cellular Magnesium. Headache 1991; 31:298-304.
  15. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of Migraine with Oral Magnesium: Results from a Prospective, Multi-Center, Placebo-Controlled and Double-Blind Randomized Study. Cephalalgia 1996; 16:257-63.
  16. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the Prophylaxis of Migraine Cephalalgia 1996;16;436-40
  17. Schoenen J, Lenaerts M, Bastings E. High-dose Riboflavin as a Prophylactic Treatment of Migraine: Results of an Open Pilot Study. Cephalalgia 1994l14:328-9
  18. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomised controlled trial. Neurology 1998; 50: 46670.
  19. Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G. High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 2004 Jul;11(7):475-7.
  20. Maria Condò, Annio Posar, Annalisa Arbizzani and Antonia Parmeggiani Riboflavin prophylaxis in pediatric and adolescent migraine. The Journal of Headache and Pain: Volume 10, Number 5 / October, 2009.

MigreLief “Original” – Effective for adults and teens ages 13 and older

Take 1 caplet in the morning and 1 caplet in the afternoon or evening with food. Allow six to seven hours between servings.

Continue daily use after 90 day build-up period to maintain benefits. Many see benefits starting within a few days.

  • Riboflavin (Vitamin B-2) can cause urine to become bright yellow. This is normal and harmless.
  • Although rare, some individuals experience transient (short term) diarrhea when taking magnesium.
  • Like most dietary supplements, use of MigreLief should be discontinued one week before any surgery.

CAUTION: Not for use during pregnancy, during lactation or by children under 13 years of age. (For children age 2-12 consider Children's MigreLief)