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Key benefits of MigreLief Original Formula supplement. MigreLief Original Formula Over 6,000 Verified 5-Star Reviews Two MigreLief Original Formula caplets. MigreLief Supplement Facts - Magnesium, Riboflavin, Feverfew for Migraines Customer review of MigreLief Original Formula supplement.
4.8
Rated 4.8 out of 5 stars
1,352 Reviews

MigreLief Original Formula

Our original patented triple-action migraine supplement with effective nutritional benefits for teen and adult migraine sufferers.
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$25.95
/ 30 day supply
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    • Trusted by Top Neurologists. Recommended by leading doctors and headache specialists for over 25 years.
    • Safe and Effective. Safe and effective for daily use by teen and adult migraine sufferers.
    • Clinically Studied. The ingredients in MigreLief Original have been extensively studied for their effectiveness.
    • Triple Action Formula. The original patented migraine supplement with Magnesium, Riboflavin, and Puracol® Feverfew.
    • Satisfaction Guaranteed.  Backed by our 90-Day Customer Satisfaction Guarantee.

Effective Nutritional Support for Migraine Sufferers*

The power of nutrients is often overlooked when considering effective solutions for migraine sufferers.* Original patented triple-therapy formula has been widely recommended by neurologists, headache specialists, and healthcare practitioners for over twenty-five years.

  • Drug-free
  • Effective and safe for long-term, daily use by adults and teens
  • Researched and developed by Akeso Health Sciences' Chief Scientific Officer, Curt Hendrix, MS, CCN, CNS, a research scientist who holds degrees in chemistry and clinical nutrition and is a Clinical Nutrition Specialist.
  • Manufactured in an established GMP facility; third party quality testing
  • NO butterbur, wheat, gluten, salt, soy, milk or dairy, nuts, corn, caffeine, or artificial flavorings or preservatives; non-GMO and vegan

MigreLief® IS A TRUSTED FORMULA THAT MAKES A DIFFERENCE

Learn More in our Health Library

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    MigreLief® products have changed lives worldwide by providing effective nutritional support to migraine sufferers. 

    Original Patented Formula with Puracol : 60 Caplets / 2 per day / 1-month supply

    Amount per 2 Tablets Daily Value
    Riboflavin (Vitamin B-2) 400mg 23,529%
    Magnesium (as citrate and oxide) 360mg 90%
    Puracol® Feverfew** (Tanacetum parthenium) 100mg *
    *No Daily Value established

    **Puracol® Feverfew (Tanacetum parthenium) is unique to MigreLief. Delivered in optimum, clinically-studied amounts, Akeso’s Puracol® is a proprietary combination of whole leaf feverfew high in naturally occurring phytochemicals and a special feverfew extract. Supports proper cerebrovascular tone and function, and platelet aggregation that can otherwise lead to vasoconstriction.*

    Magnesium—two clinically known beneficial forms of magnesium in daily amounts critical to controlling the inhibition of vasospasm and platelet aggregation in support of cerebral vascular tone*

    Riboflavin (vitamin B-2)—although necessary for human health, riboflavin is not produced by the body and, therefore, must come from our food or dietary supplementation; high doses of highly absorbable Riboflavin have been proven in clinical studies to reduce the number of neurological discomforts experienced each month and to improve mitochondrial energy deficiencies*

    MigreLief “Original” – Effective for adults and teens ages 13 and older

    Take 1 caplet in the morning and 1 caplet in the afternoon or evening with food. Allow six to seven hours between servings.

    Continue daily use after 90 day build-up period to maintain benefits. Many see benefits starting within a few days.

    CAUTION: Not for use during pregnancy, during lactation or by children under 13 years of age. (For children age 2-12 consider Children's MigreLief)

    • Riboflavin (Vitamin B-2) can cause urine to become bright yellow. This is normal and harmless.
    • Although rare, some individuals experience transient (short term) diarrhea when taking magnesium.
    • Like most dietary supplements, use of MigreLief should be discontinued one week before any surgery.


    You have a choice of MigreLief® daily formulas:

    MigreLief “Original” – Effective for adults and teens ages 13 and older

    MigreLief+M – For women experiencing hormonal/menstrual related neurologic discomfort

    Children’s MigreLief – Parents #1 choice for ages 2 - 12 years—a safe, effective, and gentle option

    Choose MigreLief-NOW for fast-acting, as-needed neurological comfort. Safe and effective for both adults and children age 2 and older. MigreLief-NOW may be combined with any of the other daily MigreLief formulas.

    1. Brown D, Gaby A, Reichert R. Clinical Applications of Natural Medicine–Migraine. NPRC Condition-Specific Monograph Series, 1997.
    2. Lawrence Review of Natural Products, September 1994.
    3. Awang DVC. Herbal Medicine, Feverfew. Canadian Pharm J 1989; 122:266-70.
    4. Heptinstall S, Awang DVC, Dawson BA, et al. Parthenolide Content and Bioactivity of Feverfew (Tanacetum parthenium). Estimation of Commercial and Authenticated Feverfew Products. J Pharm Pharmacol 1992; 44:391-5.
    5. Pugh WJ, Sambo K. Prostaglandin Synthetase Inhibitors in Feverfew. J Phrm Pharmacol 1988; 40-743-5
    6. Heptinstall S, White A, Williamson L, Mitchell JRA. Extracts of Feverfew Inhibit Granule Secretion in Blood Platelets and Polymophonuclear Leukocytes. Lancet 1985; i:1071-4.
    7. Makheja AN, Bailey JM. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostagland Leukotrienes Med 1982;8:653-60.
    8. Sumner H, Salan U, Knight DW, Hoult JRS. Inhibition of 5-Lipoxygenase and Cyclo-oxygenase in Leukocytes by Feverfew. Biochem Pharmacol 1992;43:2313-20.
    9. Johnson ES, Kadam NP, Hylands DM, Hylands PF. Efficacy of Feverfew As prophylactic Treatment of Migraine. British Med J 1985; 291:569-73.
    10. Murphy JJ. Heptinstall S, Mitchell JRA. Randomized Double-Blind Placebo-Controlled Trial of Feverfew in Migraine Prevention. Lancet 1988; ii:189-92.
    11. Altura BM. Calcium Antagonist Properties of Magnesium: Implications for Anti-migraine Actions. Magnesium 1985; 4:169-75.
    12. Ramadan NM, Halvorson H, Vande-Linde A, et al. Low Brain Magnesium in Migraine. Headache 1989; 29:590-93.
    13. Weaver K. Magnesium and Migraine. Headache 1990; 30:168.
    14. Faccinetti F, Sances G, Borella P, et al. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intra-cellular Magnesium. Headache 1991; 31:298-304.
    15. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of Migraine with Oral Magnesium: Results from a Prospective, Multi-Center, Placebo-Controlled and Double-Blind Randomized Study. Cephalalgia 1996; 16:257-63.
    16. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the Prophylaxis of Migraine Cephalalgia 1996;16;436-40
    17. Schoenen J, Lenaerts M, Bastings E. High-dose Riboflavin as a Prophylactic Treatment of Migraine: Results of an Open Pilot Study. Cephalalgia 1994l14:328-9
    18. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomised controlled trial. Neurology 1998; 50: 46670.
    19. Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G. High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 2004 Jul;11(7):475-7.
    20. Maria Condò, Annio Posar, Annalisa Arbizzani and Antonia Parmeggiani Riboflavin prophylaxis in pediatric and adolescent migraine. The Journal of Headache and Pain: Volume 10, Number 5 / October, 2009.

    Migraine Support You Deserve

    Safe for long-term, daily use by adults and teens.

    Drug Free

    Safe for long-term, daily use by adults and teens.

    Recommended by top doctors for over 25 years.

    Trusted by Neurologists

    Recommended by top doctors for over 25 years.

    All vegan, non-dairy, and gluten-free ingredients.

    Vegan

    All vegan, non-dairy, and gluten-free ingredients.

    Produced without genetic engineering or GMO ingredients.

    GMO-Free

    Produced without genetic engineering or GMO ingredients.

    Trusted by Thousands

    Reviews Disclaimer

    The product reviews below are not a substitute for professional medical advice, diagnosis, or treatment. The opinions below reflect the views and opinions expressed by our customers and not those of MigreLief, and are provided for informational purposes only. We do not verify or endorse any claims made in these reviews.

    4.8
    Rated 4.8 out of 5 stars
    Based on 1,352 reviews
    96%would recommend these products
    Total 5 star reviews: 1.1k Total 4 star reviews: 155 Total 3 star reviews: 42 Total 2 star reviews: 5 Total 1 star reviews: 2
    1,352 reviews
    • AMY G.
      Verified Buyer
      MigreLief Original Formula
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      Amazing!

      I was advised by my Neurologist to start taking high dose Magnesium and Riboflavin. A google search led me to this product. I started taking it, along with a monthly Emgality injection, and have been virtually migraine free for about a year! I have tried both on their own, and haven't been migraine free, so the combo is what's working for me. Great product, highly recommend!

    • Sharon G.
      Verified Buyer
      MigreLief+M
      Reviewing
      MigreLief+M
      I recommend this product
      Rated 5 out of 5 stars
      A lifesaver

      Amazing product recommended by my neurologist.

    • Lisa R.
      Verified Buyer
      MigreLief Original Formula
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      Great

      Love it Works good

    • Gary E.
      Verified Buyer
      MigreLief-NOW
      Reviewing
      MigreLief-NOW
      I recommend this product
      Rated 5 out of 5 stars
      Opinion

      It worked quite well for my wife.

      (Trigeminal Pain)

    • Kelly T.
      Verified Buyer
      MigreLief Original Formula
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      My subscription to deliver each, please reinstate this and send them each month again, I also need some NOW pills sent

      Wonderful

    Reviews LoadedReviews Added

    Satisfaction guaranteed

    With our 90-Day Customer Satisfaction Guarantee, you can try any of our condition-specific products for a full 90 days. If you are not satisfied, you can request a refund within 100 days of purchase date. This offer is limited to new customers and a maximum refund of 3 bottles.

    You Have a Choice of Four MigreLief Formulas

    MigreLief Original Formula Product Photo

    Daily nutritional support for teen and adult migraine sufferers*

    Safe and effective for daily use – drug free

    Triple-therapy formula

    View Product Details Add to Cart
    MigreLief-NOW Product Photo

    As-needed nutritional support for migraine or headache sufferers.

    Safe and effective for on-the-spot use – drug free

    Fast-acting formula

    View Product Details Add to Cart
    MigreLief+M Product Photo

    Daily nutritional support for menstrual/hormonal migrain sufferers*

    Safe and effective for daily use — drug free

    Triple-therapy formula PLUS 5 additional blood sugar and hormone modulating ingredients.

    View Product Details Add to Cart
    Children’s MigreLief Product Photo

    Daily nutritional support for pediatric migraine sufferers age 2-12*

    Same triple-therapy formula as Original MigreLief with doses adjusted for children.

    Same triple-action ingredients as original patented MigreLief

    View Product Details Add to Cart

    Curt Hendrix, MS, CCN, CNS

    Curt, our co-founder, is passionate about helping people with chronic health issues. He has dedicated his life to the research and development of natural medicines. With degrees in chemistry and clinical nutrition, Curt has been studying the chemistry of disease for over 30 years.


    Researchers around the world cite Curt's published scientific research. He is well known for his extensive knowledge in the field of neurological disorders, including Alzheimer's. The U.S. National Institutes of Health trusted Curt with several grants and patents.


    Curt believes that evidence-based science is the key to effective natural medicines.

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