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MigreLief-NOW MigreLief-NOW MigreLief-NOW
Rated 4.8 out of 5 stars
1,245 Reviews


A fast-acting, as-needed dietary supplement to provide neurological comfort and support for migraine sufferers.*
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    • Widely recommended by neurologists and headache specialists
    • Fast-acting, as-needed option for neurological comfort*
    • Safe and effective for all ages
    • Non-drowsy, drug-free, no side effects
    • Keep MigreLief-NOW on hand for effective on-the-spot nutritional support, or use in combination with any MigreLief daily formula for an extra boost of comfort when needed

    As Needed, Effective Nutritional Support for Migraine and Headache Sufferers*

    MigreLief-NOW provides powerful, fast acting, nutritional support for neurological and whole body comfort when you need it most.*  A safe and effective option.

    MigreLief-NOW is attributed to the scientific research that Akeso Health Sciences' Chief Scientific Officer, Curt Hendrix, performs to ensure effective combinations of ingredients at clinically recognized doses. 

    • non-drowsy formula, perfect for busy days
    • recommended by physicians and headache specialists
    • may be combined with any MigreLief "daily" formula
    • does not interfere with prescription or OTC migraine drugs
    • does not cause rebound headaches
    • does not contain butterbur, wheat, gluten, salt, soy, milk or dairy, nuts, corn, caffeine, or artificial flavorings or preservatives, non-GMO and vegan

    Learn More in our Health Library

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    MigreLief-NOW — Fast-Acting for When You Need It Most

    Serving Size: 2 Capsules •  30 Servings per Bottle
    Per 2 Caps Daily Value
    Magnesium (as citrate and oxide) 180mg 43%
    Puracol® Feverfew** (whole leaf and extract) 50mg *
    Cerevasc Ginger*** (whole root and extract) 500mg *
    Aflapin® Boswellia Serrata**** (extract) 100mg *
    *No Daily Value established

    **Puracol® is a proprietary combination of whole leaf feverfew that is high in naturally occurring phytochemicals and a special feverfew extract. Delivered in an optimum clinically studied dose; supports proper cerebrovascular tone and function, and platelet aggregation.*

    ***Cerevasc Ginger® is a proprietary combination of whole ginger rhizome and standardized ginger extract. A wide-range of known benefits including helping to promote a healthy inflammatory response; supported by many clinical studies.*

    ****Aflapin® [Boswellia Serrata] is a registered trademark of Laila Nutraceuticals. Form enhances absorption; boswellia has been historically used in traditional medicines and today shown in clinical studies to support a response to occasional pain and to promote a healthy inflammatory response.* 



    Choose MigreLief-NOW for fast-acting neurological and all-body comfort when needed. Potent, safe, and effective for men, women and children ages 2 and older. We recommend keeping MigreLief-NOW on hand at all times!

    Recommended Use:

    Ages 14-Adult: Take 3-4 capsules with food. May repeat dose in 2 hours.
    Do not exceed 8 capsules in a 24-hour period.
    Do not exceed 4 capsules if combining with a MigreLief daily formula.

    Ages 9-13: Take 1-2 capsules with food. May repeat dose in 2 hours.
    Do not exceed 4 capsules in a 24-hour period.
    Do not exceed 2 capsules if combining with a MigreLief daily formula

    Ages 2-8: Take 1 capsule with food. May repeat dose in 2 hours.
    Do not exceed 2 capsules in a 24-hour period.

    Caution: Not for use during pregnancy, during lactation, or by children under 2 years of age, or those with serious medical conditions, or while undergoing any medical procedures. Do not take if allergic to any of the ingredients, or if allergic to any of the following: plants in the Asteraceae/Compositae plant family such as ragweed, chrysanthemums, marigolds, daisies or feverfew. Like most dietary supplements, it is recommended that MigreLief be discontinued one week before any surgery. As with all dietary supplements, consult with your doctor prior to taking this product.

    Potential side effects:

    • In rare cases magnesium sensitivity may occur (gastro-intestinal upset) You may reduce the dose or discontinue use if problem persists.

    Keep out of reach of children. 

      1. Brown D, Gaby A, Reichert R. Clinical Applications of Natural Medicine–Migraine. NPRC Condition-Specific Monograph Series, 1997.
      2. Lawrence Review of Natural Products, September 1994.
      3. Awang DVC. Herbal Medicine, Feverfew. Canadian Pharm J 1989; 122:266-70.
      4. Heptinstall S, Awang DVC, Dawson BA, et al. Parthenolide Content and Bioactivity of Feverfew (Tanacetum parthenium). Estimation of Commercial and Authenticated Feverfew Products. J Pharm Pharmacol 1992; 44:391-5.
      5. Pugh WJ, Sambo K. Prostaglandin Synthetase Inhibitors in Feverfew. J Pharm Pharmacol 1988; 40-743-5.
      6. Heptinstall S, White A, Williamson L, Mitchell JRA. Extracts of Feverfew Inhibit Granule Secretion in Blood Platelets and Polymophonuclear Leukocytes. Lancet 1985; i:1071-4.
      7. Makheja AN, Bailey JM. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostagland Leukotrienes Med 1982;8:653-60.
      8. Sumner H, Salan U, Knight DW, Hoult JRS. Inhibition of 5-Lipoxygenase and Cyclo-oxygenase in Leukocytes by Feverfew. Biochem Pharmacol 1992;43:2313-20.
      9. Johnson ES, Kadam NP, Hylands DM, Hylands PF. Efficacy of Feverfew As prophylactic Treatment of Migraine. British Med J 1985; 291:569-73.
      10. Murphy JJ. Heptinstall S, Mitchell JRA. Randomized Double-Blind Placebo-Controlled Trial of Feverfew in Migraine Prevention. Lancet 1988; ii:189-92.
      11. Altura BM. Calcium Antagonist Properties of Magnesium: Implications for Anti-migraine Actions. Magnesium 1985; 4:169-75.
      12. Ramadan NM, Halvorson H, Vande-Linde A, et al. Low Brain Magnesium in Migraine. Headache 1989; 29:590-93.
      13. Weaver K. Magnesium and Migraine. Headache 1990; 30:168.
      14. Faccinetti F, Sances G, Borella P, et al. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intra-cellular Magnesium. Headache 1991; 31:298-304.
      15. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of Migraine with Oral Magnesium: Results from a Prospective, Multi-Center, Placebo-Controlled and Double-Blind Randomized Study. Cephalalgia 1996; 16:257-63.
      16. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the Prophylaxis of Migraine–A Double-Blind, Placebo-Controlled Study. Cephalalgia 1996;16:436-40.
      17. Schoenen J, Lenaerts M, Bastings E. High-dose Riboflavin as a Prophylactic Treatment of Migraine: Results of an Open Pilot Study. Cephalalgia 1994l14:328-9
      18. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomised controlled trial. Neurology 1998; 50: 46670.
      19. Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G. High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 2004 Jul;11(7):475-7.
      20. Maria Condò1, Annio Posar1, Annalisa Arbizzani1 and Antonia Parmeggiani1 Riboflavin prophylaxis in pediatric and adolescent migraine. The Journal of Headache and Pain: Volume 10, Number 5 / October, 2009
      21. Schellenberg R. Treatment for PMS with agnus castus. BMJ. 2001 Han 20;322(7279):134-7
      22. Haut-und Gesch. 1964; 36:220 Giss, G. Rothenburg,W.
      23. Ggw 1967;106:124-6 Amann W. Improvement of acne vulgaris with Agnus castus
      24. Zbl GynSkol 1959 81:701 Bleier, W.
      25. Medica Emperica 1990, 9”494-502 Bohnert, K.J. Hahs, G. Phytotherapy in Gynecology and Obstetrics (Chasteberry) Acta
      26. clin. Biochem Nutr. 1993;14:211-218 Therapeutic evaluation of the effect of biotin on hyperglycemia in patients with non-insulin dependent diabetes mellitus.
      27. 2007 Nov-Dec;47(10):1436-43 Insulin metabolism is altered in migraineurs. Cavestro, C. et al
      28. J Obstet Gynaecol 1990;97:847-52 vitamin B6 in the treatment of the premenstrual syndrome- a review, Kleijnen J. Riet GT et al
      29. Int J]. Gunn AD Vitam Nutr Res. 1985;Suppl 27:213–24 review
      30. J Int Med Res 1985;13:174-9 Controlled trial of B6 in PMS Harris RI, Deand BC
      31. Lancet 1985;1399 B6 and PMS Brush MG, Perry M.
      32. BMJ 1999;318;1375-81 Systematic Review B6 and PMS Dimmock PW et al
      33. Arch Dermatol 1974;110:130-131 B6 for premenstrual acne Snider B et al
      34. J Invest Dermatol 1942;5:143-8 B6 on resistant adolescent acne. Joliffe N et al
      35. Clin Neuropharmacol 30(1):25-38 Electrical mapping of the effect of theanine. Higgin BA et al
      36. Bio Psychol 74(1):39-45 Theanine reduces psychological and physiological stress Ozeki M et al.
      37. Biol Psychol 77(2):113-22 Effects of theanine and caffeine on cognition and mood Kimura k et al.

      Effective Nutritional Support for Migraine Sufferers*


      Drug Free

      Recommended by Neurologists



      Trusted by Thousands

      Reviews Disclaimer

      The product reviews below are not a substitute for professional medical advice, diagnosis, or treatment. The opinions below reflect the views and opinions expressed by our customers and not those of MigreLief, and are provided for informational purposes only. We do not verify or endorse any claims made in these reviews.

      Rated 4.8 out of 5 stars
      Based on 1,245 reviews
      96%would recommend these products
      Total 5 star reviews: 1k Total 4 star reviews: 150 Total 3 star reviews: 42 Total 2 star reviews: 6 Total 1 star reviews: 4
      1,245 reviews
      • Sean M.
        Verified Buyer
        I recommend this product
        Rated 5 out of 5 stars
        Part of my Regimen

        The neurologist suggested that I consider this when my migraines were painful and I did not want the standard Rx solution.

      • Lisa C.
        Verified Buyer
        MigreLief Original Formula
        MigreLief Original Formula
        I recommend this product
        Rated 5 out of 5 stars
        Highly recommended by neurologist

        My neurologist highly recommended I start taking Migrelief as the ingredients were very beneficial to people with migraines. I have been taking it for so long that I am afraid to stop in case my migraines get worse.

      • Jeffrey O.
        Verified Buyer
        MigreLief Original Formula
        MigreLief Original Formula
        I recommend this product
        Rated 5 out of 5 stars
        It works

        Bottom line it works. It would be nice if it were a little less expensive.

      • Kaye S.
        Verified Buyer
        MigreLief Original Formula
        MigreLief Original Formula
        I recommend this product
        Rated 5 out of 5 stars

        Awesome pill.

      • Marianne L.
        Verified Buyer
        MigreLief Original Formula
        MigreLief Original Formula
        I recommend this product
        Rated 5 out of 5 stars

        Thank you for awesome customer service!

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      Satisfaction guaranteed

      With our 90-Day Customer Satisfaction Guarantee, you can try any of our condition-specific products for a full 90 days. If you are not satisfied, you can request a refund within 100 days of purchase date. This offer is limited to new customers and a maximum refund of 3 bottles.

      You Have a Choice of Four MigreLief Formulas

      MigreLief Original Formula Product Photo

      Daily nutritional support for teen and adult migraine sufferers*

      Safe and effective for daily use – drug free

      Triple-therapy formula

      View Product Details Add to Cart
      MigreLief-NOW Product Photo

      As-needed nutritional support for migraine or headache sufferers.

      Safe and effective for on-the-spot use – drug free

      Fast-acting formula

      View Product Details Add to Cart
      MigreLief+M Product Photo

      Daily nutritional support for menstrual/hormonal migrain sufferers*

      Safe and effective for daily use — drug free

      Triple-therapy formula PLUS 5 additional blood sugar and hormone modulating ingredients.

      View Product Details Add to Cart
      Children’s MigreLief Product Photo

      Daily nutritional support for pediatric migraine sufferers age 2-12*

      Same triple-therapy formula as Original MigreLief with doses adjusted for children.

      Same triple-action ingredients as original patented MigreLief

      View Product Details Add to Cart

      Curt Hendrix, MS, CCN, CNS

      Curt, our co-founder, is passionate about helping people with chronic health issues. He has dedicated his life to the research and development of natural medicines. With degrees in chemistry and clinical nutrition, Curt has been studying the chemistry of disease for over 30 years.

      Researchers around the world cite Curt's published scientific research. He is well known for his extensive knowledge in the field of neurological disorders, including Alzheimer's. The U.S. National Institutes of Health trusted Curt with several grants and patents.

      Curt believes that evidence-based science is the key to effective natural medicines.