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Akeso's Age-Defying Botanical Night Serum
Rated 5.0 out of 5 stars
1 Review

Akeso's Age-Defying Botanical Night Serum

Natural and healthy antioxidant-rich nourishment for a youthful, glowing, and healthy appearance.
In Stock. Free shipping on orders over $40

    Restore your skin back to a youthful glow with Akeso's Age-Defying Botanical Night Serum – a combination of the world’s best-known moisturizing and anti-aging ingredients.

    Akeso's Age-Defying Botanical Night Serum combines retinol and powerful botanicals clinically proven to moisturize the skin and reduce the appearance of wrinkles and other signs of aging.



Retinol Liposome PF is an exfoliator and its effect of repeatedly shedding the upper dermal layer forces the skin to produce more new cells. Retinol is one of the best known and best studied of all anti-aging ingredients.

But not all retinol is created equal. Akeso's night serum contains "Retinol Liposome PF” which utilizes liposomal encapsulation technology for better and deeper penetration of the epidermal skin layer to deliver the anticipated results.

Retinol can be an unstable molecule, prone to rapid degeneration when exposed to oxygen and light. Liposomal encapsulation helps to protect, stabilize, and deliver the benefits of retinol. 

Aquaxyl™ (natural sugar derivatives Xylitylglucoside (and) Anhydroxylitol (and) Xylitol ), is a patented ingredient of Seppic Inc. in France. Derived from natural sugars, studies show that this ingredient improves water reserves and limits water loss. The product also contains Shea Butter and Sodium Hyaluronate for additional moisturizing benefits.


Stay-C® is a stabilized vitamin C derivative (sodium ascorbyl phosphate) with many documented skin benefits including reducing the look of wrinkles, skin brightening, protection from environmental exposure, and clearing acne-prone skin. Vitamin C is a potent antioxidant that protects the skin from free radicals, which can cause damage and aging.


Hyaluronic Acid is one of the world’s best moisturizers. As skin ages, it loses its ability to hold water. Hyaluronic Acid helps deliver back water to the skin cells. These moisture-saturated skin cells help your skin look firmer, tighter, and younger looking.

Matrixyl® (palmitoyl pentapeptide-4), is a patented ingredient of Sederma Inc. in France that has shown to decrease the appearance of wrinkles by 68%. 

Matrixyl® Synthe-6™ is the newest addition to the famous Matrixyl® family of peptides. Provides internal skin support to decrease the appearance of wrinkles.

Aloe Vera Leaf Juice(aloe barbadensis) - Provides a myriad of benefits for the skin including; Reducing inflammation, moisturizing and protecting the skin. Aloe's hydration properties can help to keep the skin feeling soft and supple.

Aloe contains enzymes, minerals, vitamins and other compounds that are beneficial for the skin. It is rich in vitamins A, C, and E, which are essential for healthy skin. It also contains active compounds that help to promote cell growth and reduce inflammation.

Not only does it provide a protective barrier against environmental stressors, but when used regularly, aloevera leaf juice can help to diminish the appearance of fine lines, wrinkles, and scars.

Aloe Vera Leaf Juice contain the following compounds:

  • Polysaccharides – provide Aloe with its moisturizing, emollient, and anti-inflammatory properties, as well as forming a protective barrier on the skin. 
  • Anthraquinones have antibacterial and antioxidant properties. 
  • Phytosterols – soothe and calm irritated skin while also hydrating and preventing it from trans-epidermal water loss. 
  • Glycosides – aid in healthy cell renewal and have antihistaminic (anti-allergen) characteristics, while vitamins, minerals, and necessary amino acids nourish the skin. 
  • Glycosaminoglycans (GAGs) - aids in the retention of moisture in the skin. GAGs absorb water rapidly, resulting in the fluid that fills the area between collagen and elastin fibers in the dermis, giving it turgidity. As a result, Aloevera’s GAGs are what make this natural component a wonderful complement to a skin moisturizer.

Apple Stem Cell Extract (PhytoCellTec® Malus Domestica) - Targets premature aging and fine lines. PhytoCellTec™ Malus Domestica is a liposomal preparation based on the stem cells of a rare Swiss apple. Studies showed the double activity of PhytoCellTec™ Malus Domestica:
• helps skin stem cells to maintain their characteristics and their capacity to build new tissues
• delays the appearance of aging and has an anti-wrinkle appearance effect.
Apple stem cells are a revolutionary ingredient in skincare that have been shown to have
numerous benefits for the skin. They promote the production of new skin cells, increase
collagen and elastin production, protect against UV damage, soothe irritated skin, and hydrate the skin. Studies show that apple stem cells activate your own skin stem cell regeneration, protect the cell from stress, and decrease the appearance of wrinkles.

Chamomile Flower Extract - Calms and soothes the skin. Chamomile has anti-inflammatory properties and antioxidants making it a great moisturizer and skin soother.

Chamomile is known for its abundance of flavonoids and phytochemicals. These nutrients are known to fight against harmful free radicals and speed up cell regeneration, thereby improving the appearance of fine lines, wrinkles, and scars.

Olea Europa (Olive Leaf Extract) - Cleanses the pores, absorbs excess oil, and facilitates the clearing up of acne breakouts by eliminating acne-causing bacteria. Has anti-inflammatory and antioxidant properties which help to prevent skin cell damage caused by oxidation.

Green Tea Leaf Extract - Helps improve your skin's natural moisture, brightens and evens skin tone. Green Tea Extract is an extremely powerful antioxidant containing ECGC which has strong anti-inflammatory and anti-microbial properties. It helps to fight acne, unclog pores, and reduce inflammation that makes your face look puffy. It also contains caffeine and tannins which are great at shrinking blood vessels around the eyes and shrink pores by acting as an astringent.

The combination of ingredients in Akeso's Age Defying Night Serum give your skin what it's been craving - natural and healthy antioxidant-rich nourishment for a youthful, glowing, and healthy appearance.

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Reviews Disclaimer

The product reviews below are not a substitute for professional medical advice, diagnosis, or treatment. The opinions below reflect the views and opinions expressed by our customers and not those of MigreLief, and are provided for informational purposes only. We do not verify or endorse any claims made in these reviews.

Rated 5.0 out of 5 stars
Based on 1 review
100%would recommend this product
Total 5 star reviews: 1 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
1 review
  • Janet V.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    Noticeable improvement

    I really see an improvement in my skin using this cream for just a month. It’s tighter, smoother and I see less fine lines. I actually feel younger than my 73 years!

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Satisfaction guaranteed

With our 90-Day Customer Satisfaction Guarantee, you can try any of our condition-specific products for a full 90 days. If you are not satisfied, you can request a refund within 100 days of purchase date. This offer is limited to new customers and a maximum refund of 3 bottles.

Curt Hendrix, MS, CCN, CNS

Curt, our co-founder, is passionate about helping people with chronic health issues. He has dedicated his life to the research and development of natural medicines. With degrees in chemistry and clinical nutrition, Curt has been studying the chemistry of disease for over 30 years.

Researchers around the world cite Curt's published scientific research. He is well known for his extensive knowledge in the field of neurological disorders, including Alzheimer's. The U.S. National Institutes of Health trusted Curt with several grants and patents.

Curt believes that evidence-based science is the key to effective natural medicines.

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