4.8
Rated 4.8 out of 5 stars
1,348 Reviews

MigreLief Original Formula

#1 nutritional supplement for teen and adult migraine sufferers.

  • Original patented triple-therapy formula
  • Trusted by neurologists for over 25 years
  • Clinically proven ingredients to support head comfort
Pack Size
Pack Size
Frequency
$26.95
30 day supply
90-day money back guarantee.
In Stock. Free shipping on orders over $40
Drug Free
Trusted by Doctors
Safe & Effective
Vegan &
GMO-Free

Effective Nutritional Support for Migraine Sufferers*

The power of nutrients is often overlooked when considering effective solutions for migraine sufferers.* Original patented triple-therapy formula has been widely recommended by neurologists, headache specialists, and healthcare practitioners for over twenty-five years.

  • Drug-free
  • Effective and safe for long-term, daily use by adults and teens
  • Researched and developed by Akeso Health Sciences' Chief Scientific Officer, Curt Hendrix, MS, CCN, CNS, a research scientist who holds degrees in chemistry and clinical nutrition and is a Clinical Nutrition Specialist.
  • Manufactured in an established GMP facility; third party quality testing
  • NO butterbur, wheat, gluten, salt, soy, milk or dairy, nuts, corn, caffeine, or artificial flavorings or preservatives; non-GMO and vegan

MigreLief® IS A TRUSTED FORMULA THAT MAKES A DIFFERENCE

Learn More in our Health Library

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    MigreLief® products have changed lives worldwide by providing effective nutritional support to migraine sufferers. 

    Original Patented Formula with Puracol : 60 Caplets / 2 per day / 1-month supply

    Amount per 2 Tablets Daily Value
    Riboflavin (Vitamin B-2) 400mg 23,529%
    Magnesium (as citrate and oxide) 360mg 90%
    Puracol® Feverfew** (Tanacetum parthenium) 100mg *
    *No Daily Value established

    **Puracol® Feverfew (Tanacetum parthenium) is unique to MigreLief. Delivered in optimum, clinically-studied amounts, Akeso’s Puracol® is a proprietary combination of whole leaf feverfew high in naturally occurring phytochemicals and a special feverfew extract. Supports proper cerebrovascular tone and function, and platelet aggregation that can otherwise lead to vasoconstriction.*

    Magnesium—two clinically known beneficial forms of magnesium in daily amounts critical to controlling the inhibition of vasospasm and platelet aggregation in support of cerebral vascular tone*

    Riboflavin (vitamin B-2)—although necessary for human health, riboflavin is not produced by the body and, therefore, must come from our food or dietary supplementation; high doses of highly absorbable Riboflavin have been proven in clinical studies to reduce the number of neurological discomforts experienced each month and to improve mitochondrial energy deficiencies*

    MigreLief “Original” – Effective for adults and teens ages 13 and older

    Take 1 caplet in the morning and 1 caplet in the afternoon or evening with food. Allow six to seven hours between servings.

    Continue daily use after 90 day build-up period to maintain benefits. Many see benefits starting within a few days.

    CAUTION: Not for use during pregnancy, during lactation or by children under 13 years of age. (For children age 2-12 consider Children's MigreLief)

    • Riboflavin (Vitamin B-2) can cause urine to become bright yellow. This is normal and harmless.
    • Although rare, some individuals experience transient (short term) diarrhea when taking magnesium.
    • Like most dietary supplements, use of MigreLief should be discontinued one week before any surgery.


    You have a choice of MigreLief® daily formulas:

    MigreLief “Original” – Effective for adults and teens ages 13 and older

    MigreLief+M – For women experiencing hormonal/menstrual related neurologic discomfort

    Children’s MigreLief – Parents #1 choice for ages 2 - 12 years—a safe, effective, and gentle option

    Choose MigreLief-NOW for fast-acting, as-needed neurological comfort. Safe and effective for both adults and children age 2 and older. MigreLief-NOW may be combined with any of the other daily MigreLief formulas.

    1. Brown D, Gaby A, Reichert R. Clinical Applications of Natural Medicine–Migraine. NPRC Condition-Specific Monograph Series, 1997.
    2. Lawrence Review of Natural Products, September 1994.
    3. Awang DVC. Herbal Medicine, Feverfew. Canadian Pharm J 1989; 122:266-70.
    4. Heptinstall S, Awang DVC, Dawson BA, et al. Parthenolide Content and Bioactivity of Feverfew (Tanacetum parthenium). Estimation of Commercial and Authenticated Feverfew Products. J Pharm Pharmacol 1992; 44:391-5.
    5. Pugh WJ, Sambo K. Prostaglandin Synthetase Inhibitors in Feverfew. J Phrm Pharmacol 1988; 40-743-5
    6. Heptinstall S, White A, Williamson L, Mitchell JRA. Extracts of Feverfew Inhibit Granule Secretion in Blood Platelets and Polymophonuclear Leukocytes. Lancet 1985; i:1071-4.
    7. Makheja AN, Bailey JM. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostagland Leukotrienes Med 1982;8:653-60.
    8. Sumner H, Salan U, Knight DW, Hoult JRS. Inhibition of 5-Lipoxygenase and Cyclo-oxygenase in Leukocytes by Feverfew. Biochem Pharmacol 1992;43:2313-20.
    9. Johnson ES, Kadam NP, Hylands DM, Hylands PF. Efficacy of Feverfew As prophylactic Treatment of Migraine. British Med J 1985; 291:569-73.
    10. Murphy JJ. Heptinstall S, Mitchell JRA. Randomized Double-Blind Placebo-Controlled Trial of Feverfew in Migraine Prevention. Lancet 1988; ii:189-92.
    11. Altura BM. Calcium Antagonist Properties of Magnesium: Implications for Anti-migraine Actions. Magnesium 1985; 4:169-75.
    12. Ramadan NM, Halvorson H, Vande-Linde A, et al. Low Brain Magnesium in Migraine. Headache 1989; 29:590-93.
    13. Weaver K. Magnesium and Migraine. Headache 1990; 30:168.
    14. Faccinetti F, Sances G, Borella P, et al. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intra-cellular Magnesium. Headache 1991; 31:298-304.
    15. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of Migraine with Oral Magnesium: Results from a Prospective, Multi-Center, Placebo-Controlled and Double-Blind Randomized Study. Cephalalgia 1996; 16:257-63.
    16. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the Prophylaxis of Migraine Cephalalgia 1996;16;436-40
    17. Schoenen J, Lenaerts M, Bastings E. High-dose Riboflavin as a Prophylactic Treatment of Migraine: Results of an Open Pilot Study. Cephalalgia 1994l14:328-9
    18. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomised controlled trial. Neurology 1998; 50: 46670.
    19. Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhaupl KM, Arnold G. High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. Eur J Neurol. 2004 Jul;11(7):475-7.
    20. Maria Condò, Annio Posar, Annalisa Arbizzani and Antonia Parmeggiani Riboflavin prophylaxis in pediatric and adolescent migraine. The Journal of Headache and Pain: Volume 10, Number 5 / October, 2009.

    As featured in

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    Your Partner in Proactive Migraine Care

    MigreLief provides nutritional support for migraine sufferers.

    To Begin

    Take one caplet every morning and evening for best results.

    Days 1-90

    Give your body time to absorb the essential nutrients to feel the benefits.

    90 Days Later

    Continue daily use after 90-day build-up period to maintain benefits. 

    Unique, Tested & Guaranteed

    • Developed by a Migraine Expert: Our advanced formula was created by Curt Hendrix, MS, CCN, CNS—a pioneer in natural health solutions.
    • Clinically Studied Ingredients: Formulated with magnesium, riboflavin, and Puracol® Feverfew—ingredients backed by scientific research.
    • Unique Puracol® Feverfew: A proprietary blend delivering optimal support for cerebrovascular tone and function.*
    • Satisfaction Guaranteed: Backed by our 90-Day Customer Satisfaction Guarantee.

    Original Patented Formula Trusted Worldwide

    Puracol® Feverfew

    Encourages a healthy inflammatory response, proper cerebrovascular tone and function & normal platelet aggregation.

    Magnesium

    Supports muscle relaxation, nerve function & brain health.

    Image of Riboflavin, Vitamin B-2.
    Riboflavin (Vitamin B-2)

    Promotes mitochondrial energy production & healthy brain cell function.

    Trusted By Hundreds of Thousands

    Reviews Disclaimer

    The product reviews below are not a substitute for professional medical advice, diagnosis, or treatment. The opinions below reflect the views and opinions expressed by our customers and not those of MigreLief, and are provided for informational purposes only. We do not verify or endorse any claims made in these reviews.

    4.8
    Rated 4.8 out of 5 stars
    Based on 1,348 reviews
    96%would recommend these products
    Total 5 star reviews: 1.1k Total 4 star reviews: 158 Total 3 star reviews: 43 Total 2 star reviews: 5 Total 1 star reviews: 2
    1,348 reviews
    • Mazal S.
      Verified Buyer
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      MigreLief Original Formula

      A very good product. I've been using it for years!

    • Kenwade L.
      Verified Buyer
      Reviewing
      MigreLief Starter Pack
      I recommend this product
      Rated 5 out of 5 stars
      Starter pack

      This was a good deal

    • Laura S.
      Verified Buyer
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      So helpful

      This, in combination with my preventative shot, has been a game changer for me. Highly recommend trying.

    • Jim S.
      Verified Buyer
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      Good Stuff

      All good!

    • Melissa C.
      Verified Buyer
      Reviewing
      MigreLief Original Formula
      I recommend this product
      Rated 5 out of 5 stars
      Migrelief

      I purchased it for my 16yr old son as recommended by his doctor to supplement his preventative care. I normally get it from Amazon but it was out of stock. The migrelief itself is great, no complaints but the shipping issues were. There were a few delays and we ended up receiving it the day he ran out. I had ordered it for sooner

    You Have a Choice of MigreLief Formulas

    MigreLief Original Formula Product Photo

    MigreLief Original

    MigreLief+M Product Photo

    MigreLief + M

    MigreLief-NOW Product Photo

    MigreLief Now

    Children’s MigreLief Product Photo

    Children’s MigreLief

    Star Rating
    4.8
    Rated 4.8 out of 5 stars
    1,348 Reviews
    4.8
    Rated 4.8 out of 5 stars
    1,348 Reviews
    4.8
    Rated 4.8 out of 5 stars
    1,348 Reviews
    4.8
    Rated 4.8 out of 5 stars
    1,348 Reviews
    Product Description
    Daily nutritional support for teen and adult migraine sufferers.
    Designed for women who experience hormonal migraines.
    Fast-acting, on-the-spot nutritional support when migraines strike.
    Recommended by pediatric neurologists, with child-friendly caplets for easy use.
    Safe, Effective & Drug-Free
    Clinically Backed Ingredients
    Third-Party Tested
    Shop Now Shop Now Shop Now Shop Now

    Created by the Pioneer of Migraine Supplements

    Based on scientific evidence, MigreLief’s Chief Scientific Officer, Curt Hendrix, MS, CCN, CNS, was the first to discover the unique combination of magnesium, riboflavin (vitamin B2), and Puracol® feverfew for migraine sufferers, earning him two U.S. patents.

    Passionate and driven, Curt’s mission is to empower people with better, more natural ways to support their well-being.